A pancreatic pseudocyst is a fluid-filled sac that forms on your pancreas. It can also contain tissue from the pancreas, enzymes, and blood. Pancreatic pseudocysts most often occur after a bout of pancreatitis. The cysts typically form when the ducts carrying pancreatic fluids to the intestine become blocked. Pancreatic pseudocysts don’t always show symptoms, but if you have recently had pancreatitis watch for nausea, vomiting, pain in the upper abdomen, a lump, and difficulty eating. These can be signs of pancreatic pseudocysts. Excessive use of alcohol and tobacco increases your risk for developing pancreatic pseudocysts.